The September 2022 Cascadia general election was the second monthly general election in Cascadia to elect the Governor of Cascadia and all twelve seats in the House of Representatives for one-month terms. It was held from September 16 to September 17, 2022. ViolentVampire and SayerQT were elected as the 2nd Governor and Lieutenant Governor of Cascadia. This was the second of three elections in Cascadia to not be held on the third Sunday of a month, prior to the ratification of the 2nd amendment to the first Constitution of Cascadia.
Incumbent President SayerQT did not stand for re-election. The presidential election resulted in a victory for incumbent Treasurer ViolentVampire, receiving a record 95.2% of the vote. Voter turnout was down slightly at 46.7% of registered voters. The House elections resulted in incumbents winning just half of the seats, with incumbents winning just around 52% of first-preference votes. These were also the first elections for the House of Representatives held under Proportional Representation instead of First-past-the-post, put into place by the Representation of the People Act passed in early August.